Washington State University;BAKER IDI HEART AND DIABETES INSTITUTE HOLDING LIMITED
发明人:
Buel Dantese Rodgers,Paul Gregorevic
申请号:
US15568244
公开号:
US20180112232A1
申请日:
2016.04.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.