The present subject matter relates to acompound represented by the general formula (I) or (I')or a pharmacologically acceptable salt thereof； pharmaceuticalcompositions containing at least one of thesecompounds； methods of making at least one of thesecompounds； methods of using at least one of these compoundsfor treating and/or preventing various cancersand/or proliferation disorders； methods of using at leastone of these compounds for monitoring the effectivenessof an anticancer therapy against various cancers. In oneembodiment, the subject matter relates to compoundsthat bind with a level of specificity to heat shock protein70 (Hsp70). In another embodiment, the subject matterrelates to compounds that bind with a level of specificityto inhibit both heat shock protein 70 (Hsp70) and heatshock cognate protein 70 (Hsc70).
