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Spider silk fusion protein structures for binding to an organic target
专利权人:
Spiber Technologies AB
发明人:
Hedhammar, My,Johansson, Jan,Rising, Anna,Nygren, Per-Ake
申请号:
AU2011322657
公开号:
AU2011322657C1
申请日:
2011.10.25
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
A protein structure capable of selective interaction with an organic target is provided. The protein structure is a polymer comprising as a repeating structural unit a recombinant fusion protein that is capable of selective interaction with the organic target. The fusion protein is comprising the moieties B, REP and CT, and optionally NT. B is a non-spidroin moiety of more than 30 amino acid residues, which provides the capacity of selective interaction with the organic target. REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein. CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein. NT is an optional moiety of from 100 to 160 amino acid residues and is derived from the N-terminal fragment of a spider silk protein. The fusion protein and protein structure thereof is useful as an affinity medium and a cell scaffold material.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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