Robert Kendall Morrison,Zili An,Karen Jane Meyrick Morrison,Josh Snyder,Xiao-Chi Jia
申请号:
US15085877
公开号:
US09926376B2
申请日:
2016.03.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Antibody drug conjugates (ADC's) that bind to 158P1D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in glioblastoma, lung cancer, bladder cancer, and breast cancer. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.