NIVENS, MICHAEL CHADHAM,BOUYSSOU, THIERRY,GOEGGEL, ROLF,SEITHER, PETER
申请号：
PH12014502239
公开号：
PH12014502239A1
申请日:
2014.10.03
申请国别(地区):
PH
年份:
2014
代理人:
摘要：
The present invention relates to CCR3 inhibitors of formula (1), wherein R1 is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl R2 is H, C1-6-alkyl X is an anion selected from the group consisting of chloride or ? dibenzoyltartrate j is 1 or 2. for use as a medicament for the treatment of diseases selected from dry age-related macular degeneration (dAMD), wet age-related macular degeneration (wAMD), retinopathy of prematurity (ROP), central retinal vein occlusion (CRVO), nasal polyposis, eosinophilic esophagitis, eosinophillic gastroenteritis (e.g. eosinophilic gastritis and eosinophilic ententeritis), hyper eosinophilic syndrome and Churg Strauss syndrome.
