THIOPHENE INHIBITORS OF IKK-B SERINE-THREONINE PROTEIN KINASE

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专利权人:

Alan Hastings Drummond;Richard James Testar

发明人:

Alan Hastings Drummond,Richard James Testar

申请号：

US13265848

公开号：

US20120035251A1

申请日:

2010.04.20

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention provides a compound which is (a) a thiophene carboxamide derivative of formula (IA) or (IB), or a tautomer thereof； or (b) a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof, wherein L1, A1 and W are as defined herein. The compounds are useful as IKKβ inhibitors. The compounds can thus be used in medicine, for example in the treatment of autoimmune and inflammatory diseases.

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