HARM VEENSTRA,TITIA MARTINE TRUCE MULDERS,WOUTER DE GRAAFF
申请号:
BRPI1016147
公开号:
BRPI1016147A2
申请日:
2010.05.03
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.