The subject matter described herein relates to methods, systems, and computer readable media for measuring systemic vascular resistance (SVR). In some examples, a method for measuring SVR includes determining, by a computer system coupled to a photoplethysmography (PPG) sensor and a display device, a plurality of wave parameters from a cardiac waveform signal detected by the PPG sensor, wherein the wave parameters include at least a systolic peak amplitude, a diastolic peak amplitude, and a dicrotic notch amplitude. The method includes determining, by the computer system, an SVR value based on the wave parameters. The method includes displaying the SVR value on the display device or other available screen.