The present invention relates generally to single nucleotide polymorphisms (SNP) associated with increased resistance of a rainbow trout (Oncorhynchus mykiss)to infectious pancreatic necrosis (IPN). In particular, the present invention provides methods for predicting increased resistance of a rainbow trout to infectious pancreatic necrosis (IPN)and methods for selecting a rainbow trout having increased resistant to infectious pancreatic necrosis. The present invention further provides rainbow trout, rainbow trout cells and populations thereof carrying at least one allele conferring IPN resistance ("IPN resistance allele") in their genome as well as nucleic acid molecules comprising nucleotide sequences associated with the SNPs of the present invention.
