The present invention provides a composition for producing an enteric capsule shell, which comprises an enteric polymer soluble in water, a water-soluble film forming polymer, an aggregating agent and a coagulant aid. The enteric polymer soluble in water comprises at least one hydrophobic functional group and at least one hydrophilic functional group. This invention also provides a preparation method of an enteric capsule shell, wherein the aforesaid composition is dissolved in water and heated and cooled to obtain a capsule shell preparatory liquid, a soaking needle is immersed in the capsule shell preparatory liquid and then removed and dried to obtain an enteric capsule shell. The composition for producing an enteric capsule shell of this invention can be used to make, according to the disclosed preparation method, an enteric capsule shell having excellent acid resistance characteristics, and there is no involvement of organic solvent in the course of the process, thereby making it possible to avoid the problem of organic solvent residues.本創作提供一種可製成腸溶性膠囊殼之組成物,其包含:一可水溶之腸溶性高分子、一水溶性成膜高分子、一凝集劑與一助凝劑,該可水溶之腸溶性高分子包含至少一疏水性官能基與至少一親水性官能基。本創作另提供一種腸溶性膠囊殼的製備方法,其將前述組成物溶於水後經加熱並冷卻以得一膠囊殼預備液,浸泡一浸泡針於該膠囊殼預備液後再移除並乾燥可得一腸溶性膠囊殼。本創作的可製成腸溶性膠囊殼之組成物依腸溶性膠囊殼的製備方法可製備出一腸溶性膠囊殼,其具有優異的抗酸特性,且製程過程中無有機溶劑參與,因此可避免有機溶劑殘留的問題。無
