POLYPEPTIDE CIBLE DE NAV1.9, ANTICORPS ET FRAGMENT D'ANTICORPS COMBINES A CELUI-CI, ET COMPOSITION PHARMACEUTIQUE ASSOCIEE

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专利权人:

WUHAN UNIVERSITY

发明人:

YANG, DAICHANG

申请号：

CA3062486

公开号：

CA3062486A1

申请日:

2018.02.07

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention provides an antibody or antibody fragment thereof for atargeted cytomembrane voltage-gated sodium channel a subunit Nav 1.9. Thespecificbinding target is a S3-4 ring of a voltage sensor paddle of a domain II of thevoltage-gated sodium channel a subunit. The antibody or antibody fragmentthereofis able to inactivate a voltage sensor valve, to make sodium ions unable toenter nervecells normally, thereby achieving the effect of treating and relieving pains.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/