POLYPEPTIDE CIBLE DE NAV1.9, ANTICORPS ET FRAGMENT D'ANTICORPS COMBINÉS À CELUI-CI, ET COMPOSITION PHARMACEUTIQUE ASSOCIÉE

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专利权人:

Wuhan University

发明人:

申请号：

EP18758448.7

公开号：

EP3594234A1

申请日:

2018.02.07

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention provides an antibody or antibody fragment thereof for a targeted cytomembrane voltage-gated sodium channel α subunit Nav1.9. The specific binding target is a S3-4 ring of a voltage sensor paddle of a domain II of the voltage-gated sodium channel α subunit. The antibody or antibody fragment thereof is able to inactivate a voltage sensor valve, to make sodium ions unable to enter nerve cells normally, thereby achieving the effect of treating and relieving pains.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/