PROBLEM TO BE SOLVED: To provide an improved agent and a method for treatment of a disease associated with synucleinopathy, including a Lewy body of alpha-synuclein in the brain of a patient.SOLUTION: The method includes administering the agent that induces a beneficial immunogenic response against the Lewy body. The method is particularly useful for prophylactic and therapeutic treatment of Parkinsons disease.COPYRIGHT: (C)2012,JPO&INPIT【課題】患者の脳内のα-synucleinのLewy小体を含む、synuclein病と関連する疾患の治療のための改善された物質および方法の提供。【解決手段】Lewy小体に対して有益な免疫原性応答を引き起こす物質の投与。本法は、パーキンソン病の予防的処置および治療的処置に特に有用である。【選択図】なし