Branstrom, Arthur,Josyula, Vara Prasad Venkata Nagendra,Arnold, Michael Andrew,Gerasyuto, Aleksey I.,Karp, Gary,Wang, Jiashi,Chen, Guangming,Ginzburg, Olya,Huang, Song,Narasimhan, Jana,Peddi, Srinivas
申请号:
AU2012302011
公开号:
AU2012302011A1
申请日:
2012.08.29
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present description relates to compounds and forms and pharmaceutical compositions thereof and methods for use thereof to treat or ameliorate bacterial infections caused by wild-type and multi-drug resistant Gram-negative and Gram-positive pathogens. The present description further relates to a compound having activity toward wild-type and MDR bacteria. The present description also relates to a compound having activity against quinolone-resistant Gram-negative strains (including MDR strains) as well as antibacterial activity to MDR resistant Gram-positive pathogens (including MRSA strains).