TARGETING GENE AMPLIFICATION IN CANCER USING TRIPLEX FORMATION AS A THERAPEUTIC STRATEGY

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专利权人:

Yale University

发明人:

Faye A. Rogers

申请号：

US16683205

公开号：

US20200190211A1

申请日:

2019.11.13

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Disclosed herein are methods and agents for the treatment of cancer using p53-independent apoptosis to reduce the number of p53-depleted or p53-mutated cancer cells that have amplified HER2 gene. Also disclosed herein are methods and agents for the treatment of HER2-positive cancer in individuals with Li-Fraumeni Syndrome.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/