Jian Ge,Jianyi Ma,Guangya Xiang,Wei Wang,Chaodong Wang
申请号：
US15123961
公开号：
US09708306B2
申请日:
2015.03.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention belongs to the technical field of pharmaceutical chemistry, and particularly pertains to benzimidazole derivatives, and preparation process and pharmaceutical uses thereof. Benzimidazole derivatives include Ligustrazine and NO donor derivatives. The kind of the compounds can rapidly release Ligustrazine or No in vivo, so that they can produce effective synergetic effects with Azilsartan, to enhance the anti-hypertension effect, and reduce adverse effects, and the released Ligustrazine can produce ideal protection to patients livers and kidneys, thereby filling blanks in the prior art.
