Salt of (S) - 3 - (6 - (4-methylphenyl) - pyridin - 3 - iloxi) - 1 - aza Bicyclo [2.2.2] octane; Pharmaceutical composition; Preparation method; prodcucion process of Salt and its Precursors; and Method for Prevention, Treatment and / or delay of progression of a disease or condition such as Psychiatric Disorders Atricos or neurodegenerative.
KARPINSKI, PIOTR H.,WAYKOLE, LILADHAR MURLIDHAR,VILLHAUER, EDWIN BERNARD,PRASHAD, MAHAVIR,SUTTER, BERTRAND,MARTERER, WOLFGANG,VIVELO, JAMES ANTHONY,BIANCHI, JEAN-CLAUDE,WU, RAEANN,HAR, DENIS,PIGNONE,
申请号:
CL2014000119
公开号:
CL2014000119A1
申请日:
2014.01.15
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
The present invention relates to a process for the production of a compound of formula I ((R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane) or a salt thereof and to a process for the production of a compound of formula II (5-chloro-2-(4-methylphenyl)pyridine ) or a salt thereof, which is used as an intermediate in the preparation of the compound of formula I.Sal de fumarato, maleato, cloruro, fosfato, succinato o malonato de (R)-3-(6-(4-metilfenil)-piridin-3-iloxi)-1-aza-biciclo[2.2.2] octano; formas cristalinas; composiciones farmacéuticas; procesos de preparación, y uso de éstas en la preparación de medicamentos para el tratamiento de condiciones relacionadas con a7nAChR