Provided is a method for producing a pharmaceutical preparation containing a calcium antagonist and an angiotensin II receptor antagonist as active ingredients, said method being characterized by comprising a granulation step of granulating the calcium antagonist and the angiotensin II receptor antagonist together or separately without using water. A pharmaceutical preparation produced by the method can have an elution profile close to the elution profile of a commercially available calcium antagonist preparation and the elution profile of a commercially available angiotensin II receptor antagonist preparation.本發明係提供一種醫藥製劑之製造方法,其係含有鈣拮抗劑及血管張力素II受體拮抗劑作為有效成分的醫藥製劑之製造方法,其特徵為包含不使用水地將鈣拮抗劑及血管張力素II受體拮抗劑一起或分別造粒的造粒步驟。藉由此方法所製造出的醫藥製劑,係可實現與市售之鈣拮抗劑製劑及血管張力素II受體拮抗劑製劑各自的溶出輪廓(elution profile)接近之溶出輪廓。
