Provided is a pharmaceutical preparation containing a calcium antagonist and an angiotensin II receptor antagonist as active ingredients, and containing 5 mass% or more of a disintegrant, the pharmaceutical preparation being characterized in that at least the calcium antagonist has the form of a solid dispersion. The pharmaceutical preparation improves the storage stability of the angiotensin II receptor antagonist. The pharmaceutical preparation has an elution profile similar to those of commercially available calcium antagonist preparations and commercially available angiotensin II receptor antagonist preparations.本發明係提供一種醫藥製劑,其特徵為含有作為有效成分之鈣拮抗劑及血管張力素II受體拮抗劑、與5質量%以上之崩解劑,且至少鈣拮抗劑為固體分散體之形態。此醫藥製劑係可提昇血管張力素II受體拮抗劑之保存安定性。此外,該醫藥製劑係可實現與市售之鈣拮抗劑製劑及血管張力素II受體拮抗劑各自的溶出輪廓(elution profile)接近之溶出輪廓。
