Thorsten Wilhelm;Dominic De Souza;Hans-Peter Spitzenstaetter;Michael Oberhuber;Martin Langner;Hubert Sturm;Martin Albert;Joerg Salchenegger
发明人:
Michael Oberhuber,Joerg Salchenegger,Dominic De Souza,Martin Albert,Thorsten Wilhelm,Martin Langner,Hubert Sturm,Hans-Peter Spitzenstaetter
申请号：
US13697806
公开号：
US09040539B2
申请日:
2011.05.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y3—NH2； of formula (IIa) 0=C═N—Y0 and/or of formula (IIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).
