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PROCESS FOR THE PREPARATION OF PLEUROMUTILINS
专利权人:
NABRIVA THERAPEUTICS AG
发明人:
RIEDL, Rosemarie,HEILMAYER, Werner,SPENCE, Lee
申请号:
TN2012000506
公开号:
TN2012000506A1
申请日:
2012.10.23
申请国别(地区):
TN
年份:
2014
代理人:
摘要:
Process for the preparation of a Compound of formula I in the form of a single stereoisomer in crystalline form, comprising deprotecting the amine group in a Compound of formula IIa or in a mixture of a compound of formula IIa With a compound of formula IIb and isolating a Compound of formula I from the reaction mixture Compounds and salts of Compounds of formula I in crystalline form pharmaceutical compositions comprising such salts processes for the preparation of intermediates and intermediates in a process for the preparation of a Compound of formula I.
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