Sulfated alginate hydrogels for cell culture and therapy

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专利权人:

ETH Zurich

发明人:

Zenobi-Wong Marcy,Palazzolo Gemma,Mhanna Rami,Becher Jana,Moller Stefanie,Schnabelrauch Matthias

申请号：

US201314441177

公开号：

US9937257(B2)

申请日:

2013.11.04

申请国别(地区):

美国

年份:

2018

代理人:

JMB Davis Ben-David

摘要：

The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.

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