Zachary T. Ball,Rituparna Kundu,Brian V. Popp,Dean R. Madden,Patrick R. Cushing
申请号:
US13916359
公开号:
US09045527B2
申请日:
2013.06.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods for targeting a protein by providing an inhibitor covalently linked to a rhodium(II) complex, introducing the inhibitor to the target protein and allowing the inhibitor and protein to interact. The rhodium(II) complex covalently linked to the inhibitor binds the target protein both inorganically and organically and forms stabilizing secondary contacts between the rhodium(II) complex and the protein.