SMALL- MOLECULE INHIBITORS TARGETING G-PROTEIN-COUPLED RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS

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专利权人:

发明人:

Yi Zheng,Matthew Wortman

申请号：

US15644476

公开号：

US20170349553A1

申请日:

2017.07.07

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided are inhibitors of Rho GTPase activation, and, in particular, compounds that inhibit RhoA activation by an RhoGEF. Also provided are related pharmaceutical compositions and methods. Also provided are methods of inhibiting Rho GTPase activation. Also provided are methods of screening for compounds that inhibit Rho GTPase activation by a RhoGEF.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/