DE FERRA LORENZO,AMMIRATI ETTORE,ANDREASSI SIMONA,ANNIBALDI MAURO,MANDELLI LUCA,PINTO BARBARA,STRACQUALURSI FELICE
申请号：
IN201717037567
公开号：
IN201717037567A
申请日:
2017.10.24
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to a process for the preparation of a polysaccharide composed of D xylose units of formula (III) linked together via beta 1 4 glycosidic bonds wherein R is hydrogen or acetyl R is hydrogen acetyl or a 4 O methyl glucuronic acid unit wherein when R is a 4 O methyl glucuronic acid unit the R group on the same saccharide unit is defined as G wherein G is hydrogen or acetyl and wherein the sugar unit at the reducing end of such polysaccharide is xylose lyxose or xylulose said process comprising the following steps: selective deacetylation of xylan extracted from beech wood； and isomerization of the selectively deacetylated xylan achieved in step or the following steps: isomerization of xylan extracted from beech wood； and selective deacetylation of isomerized xylan achieved in step. The process is useful for the preparation of pentosan polysulfate or pharmaceutically acceptable salts thereof for pharmaceutical use.
