An oncogene therapeulic drug which contains a carrier cell having been infected with an oncolylic virus so as to treat a tumor cell wilh the vims within the living body. As the carrier cell, any of an A59 cel4l, a 293 cell, an SW626 cell and an 1IT-3 cell showing a potent antilumor effect is used. Because of using such a cell having a high antitumoreffect both in vitro and in viva as the carrier cell, an enhanced anlilnmor effect can be established compared with conventional carrier cells.