MARK T. BILODEAU,KAUSIK K. NANDA,B. WESLEY TROTTER
申请号:
BRPI0809492
公开号:
BRPI0809492A2
申请日:
2008.04.03
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The present invention is directed to therapeutic agents of the formula (I) which are atypical antipsychotics and which are useful in the treatment of neurological and psychiatric disorders associated with dopamine D2 and serotonin 5-HT2A neurotransmission dysfunction. wherein; R1 is C1-6alkyl, which is unsubstituted or substituted with 1-6 fluoro, wherein R1 and the hydroxyl group on the ring are attached to the same carbon atom; or a pharmaceutically acceptable salt thereof.