Mark T. Bilodeau;Kausik K. Nanda;B. Wesley Trotter
发明人:
Mark T. Bilodeau,Kausik K. Nanda,B. Wesley Trotter
申请号:
US12530944
公开号:
US08252799B2
申请日:
2008.04.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to therapeutic agents of the formula (I) which are atypical antipsychotics and which are useful in the treatment of neurological and psychiatric disorders associated with dopamine D2 and serotonin 5-HT2A neurotransmission dysfunction. wherein; R1 is C1-6alkyl, which is unsubstituted or substituted with 1-6 fluoro, wherein R1 and the hydroxyl group on the ring are attached to the same carbon atom; or a pharmaceutically acceptable salt thereof.