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METABOLITE DETECTION SYSTEM AND ITS OPERATION PROCEDURE
专利权人:
КОНИНКЛЕЙКЕ ФИЛИПС Н.В. (NL)
发明人:
ЯНГ Баолиан (NL)
申请号:
RU2015114570
公开号:
RU2015114570A
申请日:
2013.09.09
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A magnetic resonance (MR) system for detecting concentrations of one or more metabolites in a volume of interest (VOI), the system comprising: at least one controller configured to: apply to the VOI a local spectroscopy sequence at a selected point (PRESS) with multiquantum filter (MQF), containing the first and second 90-degree radio frequency (RF) pulses, the third 90-degree RF pulse, the first and second 180-degree adiabatic pulses and a composite pulse sequence with a two-band delay, h alternating with nutation, for adapted excitation (DANTE) with a central frequency oriented to Cr and having a plurality of N block pulses, the DANTE pulse sequence being located between the first and second 90-degree RF pulses, and the first and second 180-degree pulses adiabatic pulses are located in time after the third 90-degree RF pulse; detection of the free induction decay signal (FID) of the MR emitted by the VOI; and reconstructing the detected FID MR signal to obtain metabolite spectrum information. 2. The system of claim 1, wherein each of the first and second 90-degree RF pulses has an unbalanced waveform of the SINC type (Spredrex type). 3. The system of claim 1, wherein the third 90 degree RF pulse has a SINC waveform with an excitation bandwidth of 120 Hz. The system of claim 1, wherein the first and second 180-degree adiabatic pulses are in the form of a pulse type signal oit_800_6500.5. The system of claim 1, wherein the DANTE pulse sequence is determined by two or more of the following parameters: PD_tot = 1.0 / BW, τ = 0.5 / BW_side, N = PD_tot / τ, Flip = 2 * Flip_tot / N, θ = -4 * τ * BW_diff * 180 °, and Phase_even = (N / 2-1) θ, (N / 2-2) θ, ... θ, 0, and Phase Odd_Pulse = 0 where BW refers to the excitation band of the pulse sequence of the individual band,1. Магнитно-резонансная (MR) система для обнаружения концентраций одного или более метаболитов в интересующем объеме (VOI), причем система содержит:по меньшей мере один контроллер, выполненный с возмож
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