In a method and a control device for operation of a magnetic resonance tomography system to generate image data, multiple of slices in an examination subject are initially excited at a first time interval by a respective RF slice excitation pulse of a series of spatially selective slice excitation pulses. An RF refocusing pulse is then emitted at a second time interval after the first excitation pulse or after the last excitation pulse of the series of RF slice excitation pulses. At least one additional RF refocusing pulse is emitted at a third time interval after a preceding RF refocusing pulse. The third time interval is twice as long as the second time interval. The width of the RF refocusing pulses is selected to generate a number of chronologically separate echo signals per RF refocusing pulse for simultaneous refocusing of all excited slices.