This document discusses, among other things, a system for guiding a medical instrument within a body of a subject. The system includes a generic anatomical representation of at least a portion of the subject, a processing device, and a display device communicatively coupled to the processing device. The processing device is configured to determine a position of the medical instrument relative to the generic anatomical representation based on a position of the medical instrument relative to the subject. The display device configured to display the generic anatomical representation and a representation of the position of the medical instrument relative to the generic anatomical representation.