ROBERTS, BRUCE L.,SHANKARA, SRINIVAS,BRONDYK, WILLIAM HAROLD,SIDERS, WILLIAM M.
申请号：
MYPI 2011005455
公开号：
MY160126A
申请日:
2010.05.13
申请国别(地区):
MY
年份:
2017
代理人:
摘要：
THE PRESENT INVENTION RELATES TO HUMANIZED IMMUNOGLOBULINS, MOUSE MONOCLONAL ANTIBODIES AND CHIMERIC ANTIBODIES THAT HAVE BINDING SPECIFICITY FOR HUMAN CD52. THE PRESENT INVENTION FURTHER RELATES TO A HUMANIZED IMMUNOGLOBULIN LIGHT CHAIN AND A HUMANIZED IMMUNOGLOBULIN HEAVY CHAIN. THE INVENTION ALSO RELATES TO ISOLATED NUCLEIC ACIDS, RECOMBINANT VECTORS AND HOST CELLS THAT COMPRISE A SEQUENCE WHICH ENCODES A HUMANIZED IMMUNOGLOBULIN OR IMMUNOGLOBULIN LIGHT CHAIN OR HEAVY CHAIN, AND TO A METHOD OF PREPARING A HUMANIZED IMMUNOGLOBULIN. THE HUMANIZED IMMUNOGLOBULINS CAN BE USED IN THERAPEUTIC APPLICATIONS TO TREAT, FOR EXAMPLE, AUTOIMMUNE DISEASE, CANCER, NON-HODGKIN’S LYMPHOMA, MULTIPLE SCLEROSIS AND CHRONIC LYMPHOCYTIC LEUKEMIA.
