PROBLEM TO BE SOLVED: To provide a new cellular life extending agent, especially a vascular endothelial cellular life span extending agent, and a telomerase activator.SOLUTION: The new cellular life span extending agent, particularly an agent for extending the life span of an endothelial cell, and the telomerase activator, each comprising an extract derived from a plant belonging to the genus Cinnamomum, Lauraceae family, i.e., cinnamon bark or cassia, are provided. These agents are each a pharmaceutical effective for preventing and ameliorating various diseases caused by cellular aging and aging, namely, various inflammatory diseases, immunological diseases, lifestyle-related diseases, etc., for example, various infectious diseases, articular rheumatism, gout, hypertension, diabetes, arteriosclerosis, hyperlipemia, obesity, organ dysfunction, etc.COPYRIGHT: (C)2012,JPO&INPIT【課題】新規な、細胞寿命延長剤、特に血管内皮細胞寿命延長剤、及びテロメアーゼ活性化剤の提供。【解決手段】クスノキ科ニッケイ属植物由来,すなわちケイシ(桂枝)又はケイヒ(桂皮)由来の抽出物からなる、新規な、細胞寿命延長剤、特に血管内皮細胞寿命延長剤、及びテロメアーゼ活性化剤で、細胞老化に起因する種々の疾患および老化、すなわち種々の炎症性疾患、免疫性疾患、成人病など、例えば、種々の感染症、関節リウマチ、痛風、高血圧、糖尿病、動脈硬化症、高脂血症、肥満、臓器機能不全などの予防、改善に有効な医薬品。【選択図】図1