The present invention provides a medicine composition for treating muscular atrophy and myasthenia gravis caused by motor neuron diseases, progressive muscular dystrophy, congenital myopathy and the like, as well as to a method of preparation of the same. The medicine composition comprises active ingredients extracted from the traditional Chinese herbs as follows: 1-10 parts by weight of Ginseng and 1-10 parts of Epimedium. The medicine composition can antagonize an inhibition to the regeneration capacity of the nerve terminals caused by serum in patients having amyotrophic lateral sclerosis, promote the regeneration and restoration of the damaged nerve terminals, improve swimming endurance capacity of experimental animals, enhance muscle strength significantly, inhibit significantly the increase of creatine phosphate kinase activity in mice with the muscular fatigue, and protect the function of skeletal muscles.
