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ANTIMICROBIAL GEL FORMULATIONS COMPRISING AN HALOGENATED AMINE COMPOUND DISPERSED IN A POLY(ACRYLIC ACID) WATER-SWELLABLE POLYMER
专利权人:
NOVABAY PHARMACEUTICALS; INC
发明人:
WANG, LU,NAJAFI, AZAR,MEMARZADEH, BAHRAM,SHARMA, KULDEEPAK,HO, KIM, PHUONG
申请号:
NZ59087809
公开号:
NZ590878A
申请日:
2009.08.12
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
590878 Disclosed is a formulation comprising an halogenated amine compound of Formula (I), which is dispersed in a poly(acrylic acid) and/or a poly(ethylene oxide) water-swellable polymer and wherein the compound is 90% stable for at least 30 days at about 25 degrees C. Specific examples of compounds of Formula (I) include: N,N-dichloro-2,2-dimethyltaurine, N-chloro-2,2-dimethyltaurine, N-chloro-4-amino-4-phosphonobutyric acid, N,N-dichloro-leucine boronic acid; 3-(dichloroamino)-N,N-diethyl-N,3-dimethylbutan-1-aminium chloride; and 3-(dichloroamino)-N,N,N-triethyl-3-methylbutan-1-aminium chloride; The formulations are useful for the manufacture of a medicament for the treatment of an infection caused by a bacterial, a microbial, a sporal, a fungal or a viral activity.
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