A device (10) for mixing and dispensing bone cement includes a mixing cylinder (20), in which a mixing plunger (21) is arranged, the mixing plunger (21) being axially movable by an actuation rod (50) guided out in a sealed manner at a first cylinder end (30). A sealing plunger (42) is arranged in a region of the first cylinder end (30), is axially movable on the actuation rod (50) and seals the mixing cylinder (20) in a gas-tight manner. A sterilization plunger (41) is arranged in the region of the first cylinder end (30) between the mixing plunger (21) and the sealing plunger (42), is axially movable on the actuation rod (50) separately from the sealing plunger (42), and seals the mixing cylinder (20) in a gas-permeable manner. The sterilization plunger (41) and the sealing plunger (42) form a two-part plunger system (40).
