The invention relates to a device (10) for mixing and dispensing bone cement having a mixing cylinder (20), in which a mixing plunger (21) is arranged, whereby the mixing plunger (21) is axially movable by means of an actuation rod (50) that is guided out in a sealed manner at a first cylinder end (30), and having a sealing plunger (42) that is arranged in the region of the first cylinder end (30) and is axially movable on the actuation rod (50) and seals the mixing cylinder (20) in a gas-tight manner. According to the invention, a sterilization plunger (41) is arranged in the region of the first cylinder end (30) between the mixing plunger (21) and the sealing plunger (42) and is axially movable on the actuation rod (50) separately from the sealing plunger (42) and seals the mixing cylinder (20) in a gas-permeable manner, whereby the sterilization plunger (41) and the sealing plunger (42) form a two-part plunger system (40).