A system of determining physiological state includes a physiological measuring device configured to measure at least one physiological parameter of a user, a user interface configured to receive at least one physiological information of the user, and a processing unit coupled to the physiological measuring device and the user interface, and configured to determine at least one normal threshold and at least one abnormal threshold of the at least one physiological parameter according to the at least one physiological information, and determine a physiological state of the user is normal or abnormal according to the at least one physiological parameter, the at least one normal threshold and the at least one abnormal threshold.