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PH 7 INJECTABLE SOLUTION COMPRISING AT LEAST ONE BASIC INSULIN WITH A PI COMPRISED FROM 5.8 TO 8.5 AND A CO-POLYAMINOACIDE BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS
专利权人:
ADOCIA
发明人:
Alexandre GEISSLER
申请号:
US16212960
公开号:
US20190274953A1
申请日:
2018.12.07
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A composition is in the form of an injectable aqueous solution, the pH of which is comprised from 6.0 to 8.0, and includes at least: insulin glargine, a co-polyamino acid bearing carboxylate charges and hydrophobic Hy radicals, the co-polyamino acid being made of glutamic or aspartic units and the hydrophobic Hy radicals from following formula I below:*GpRrGpAaGpC)p ; ; Formula IThe composition does not include a basal insulin whose isoelectric point pI is from 5.8 to 8.5. A composition further includes prandial insulin.
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