Soo-Jin Choi,Byung-Goo Lee,Han-Kuk Lee,Young-Mook Lim,Wol-Young Kim,Joon-Hwan Lee
申请号:
US13132791
公开号:
US08541620B2
申请日:
2009.10.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline of Z isomer of iopromide and a method for preparing a composition comprising the crystalline Z isomer of iopromide.