CRAIG P. SMITH,MICHEL P. RATHBONE,MARGARET PETTY,DAVID RAMPE
申请号:
MYPI 20020518
公开号:
MY157745A
申请日:
2002.02.15
申请国别(地区):
MY
年份:
2016
代理人:
摘要:
N-(PYRIDINYL)-1H-INDOL-1-AMINES OF FORMULA I PROVIDE A UNIQUE COMBINATION OF BLOCKING PROPERTIES FOR BOTH THE POTASSIUM AND SODIUM CHANNELS. THESE COMPOUNDS ARE USEFUL FOR THE TREATMENT OF DEMYELINATING DISEASES AND CONDITIONS SUCH AS MULTIPLE SCLEROSIS, SPINAL CORD INJURY, TRAUMATIC BRAIN INJURY AND STROKE. THE COMPOUNDS ARE ALSO USEFUL FOR STROKE REHABILITATION, THE TREATMENT OF BLADDER IRRITATION AND DYSFUNCTION, AND THE TREATMENT OF NEUROPATHIC PAIN AND CHEMOKINE-INDUCED PAIN.