PROBLEM TO BE SOLVED: To provide a heart-lung machine capable of varying the flow of blood similarly to the variation of the flow of the blood by pulsation of an actual heart, and a control method of the heart-lung machine.SOLUTION: A heart-lung machine 1 includes a tube part 13 for circulating the blood of a subject, and a blood feed pump 30 for moving the blood inside the tube part. At the tube part on the downstream side of the blood feed pump, a valve part 52 for closing the flow of the blood is formed, also a blood amount detection part 52 for detecting a blood amount staying between the valve part and the blood feed pump by the closure of the valve part is provided, and the valve part is opened and closed on the basis of detection information of the blood amount detection part.COPYRIGHT: (C)2014,JPO&INPIT【課題】本発明は、実際の心臓の拍動による血液の流れの変動と同様に血液の流れを変動させることができる人工心肺装置及び人工心肺装置の制御方法を提供すること。【解決手段】対象者の血液を環流させるための管部13と、この管部内の血液を移動させるための血液送液用ポンプ30と、を備え、血液送液用ポンプの下流側の管部に、血液の流れを閉塞する弁部52が形成されると共に、この弁部の閉塞により弁部と血液送液用ポンプの間で滞留する血液量を検知する血液量検知部52を有し、血液量検知部の検知情報に基づいて、弁部を開閉させる構成となっている人工心肺装置1。【選択図】図1