Systems and methods for determining validity of physiological data according to an embodiment of the present invention include a patient sensor configured to acquire patient data from a patient, wherein the patient data is physiological and an environmental sensor configured to acquire environmental data related to validity of the patient data, wherein a value of the environmental data has a clinical effect on the validity of the patient data but not on performance of the environmental sensor a control/monitoring system, wherein the control/monitoring system is configured to determine whether the environmental data satisfies one or more conditions indicative of the validity of the patient data and to flag the patient data that is invalid based on the determination.