[Problem] The purpose of the present invention is to provide a drug portion packaging device whereby high-quality printing can be applied to a portion packaging paper without a support stage or the like for the portion packaging paper being provided, while the drug portion packaging device is provided with a printing unit for jetting ink and printing. [Solution] A drug portion packaging device 10 has a drug feeding unit 20, a packaging unit 30, a portion packaging paper conveyance unit 40, and a printing unit 60. The printing unit 60 has an ink ejection unit 62 configured so as to be capable of ejecting ink downward. A conveyance path T of the portion packaging paper conveyance unit 40 has an intersecting-direction conveyance unit T1 for conveying portion packaging paper S in a direction intersecting with the ejection direction of the ink, and a first conveyance direction switching unit 46 and second conveyance direction switching unit 48 for changing the conveyance direction of the portion packaging paper S on an upstream side and a downstream side, with respect to the intersecting-direction conveyance unit T1, in the conveyance direction of the portion packaging paper S. The ink ejection unit 62 is arranged in a position separated a predetermined distance upward from the intersecting-direction conveyance unit T1.