Memorial Sloan-Kettering Cancer Center;Eureka Therapeutics, Inc.
发明人:
申请号:
EP17739080.4
公开号:
EP3402518A4
申请日:
2017.01.13
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The presently disclosed subject matter provides antigen-binding proteins (e.g., chimeric antigen receptors) and antibodies or antigen-binding portions thereof that bind to a Foxp3 peptide/MHC molecule complex. Such antibodies, fusion proteins and conjugates thereof are useful for inhibiting regulatory T cells and treating cancers.