A movement assistive device includes a vertical lift module and a horizontal extension module. The vertical lift module has a lift table vertically movable upward and downward. The horizontal extension module is arranged atop the lift table to move upward and downward along with the lift table and can be driven to switch horizontally between a first state and a second state. A wheelchair equipped with the movement assistive device is also disclosed. With the movement assistive device, the wheelchair can be vertically lifted and lowered as well as be horizontally displaced, and can therefore be conveniently moved from a ground surface onto a carrier and vice versa.