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Bicyclic pyrimidine derivative
专利权人:
DAINIPPON SUMITOMO PHARMA CO.; LTD.
发明人:
SUWA, ATSUSHI,TAKADA, TAKASHI,NISHIDA, TOMOAKI
申请号:
TW100149004
公开号:
TW201245190A
申请日:
2011.12.27
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The object of the present invention is to provide a compound or a physiologically acceptable salt thereof which has a MGAT inhibitory effect and is useful as a medicament, and a pharmaceutical composition comprising the same. A bicyclic pyrimidine compound of formula (I): wherein R1 is optionally substituted lower alkyl, etc., R2 is hydrogen atom, etc., R3 is hydrogen atom, etc., R4 and R5 are each independently hydrogen atom, etc., X is oxygen atom, etc., Y is -N(R9)C(=Z)- in which R9 is hydrogen atom, etc., Z is oxygen atom, etc., etc., m is 1, n is 2, or a physiologically acceptable salt thereof.
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