Grace Mann,Naing Aay,Arlyn Arcalas,S. David Brown,Wai Ki Vicky Chan,Jeff Chen,Hongwang Du,Sergey Epshteyn,Timothy Patrick Forsyth,Adam A. Galan,Tai Phat Huynh,Mohamed Abdulkader Ibrahim,Henry William
申请号:
US11992224
公开号:
US08440663B2
申请日:
2007.01.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to certain pyrimidine derivative inhibitors of JAK-2, having Formula (I): wherein D, E, L, Z, R1, R2, R25, and n1 are as defined in the specification, pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof.