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Transdermal Delivery of Phenethylamine Monoamine Releasers
专利权人:
The Corporation of Mercer University
发明人:
Kevin S. Murnane,Ajay K. Banga,Sindhu S. Ganti,Ying Jiang,Ashana Puri
申请号:
US16346180
公开号:
US20190298661A1
申请日:
2017.10.31
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Transdermal patches and transdermally applyable pharmaceutical compositions containing an effective amount of at least one drug are disclosed. The at least one drug may be: (a) phenmetrazine; (b) 4-benzylpiperidine; (c) 3-flouroamphetamine; (d) a DA/NE releaser compound having formula (I): wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 is independently hydrogen, a halogen, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted alkoxy group, and when one or more substituents is present on an alkyl group, an alkoxy group, or both, each substituent is independently a halogen; or (e) any combination thereof. Methods of making transdermal patches and transdermally applyable pharmaceutical compositions and methods of using transdermal patches and transdermally applyable pharmaceutical compositions are also disclosed.
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