The invention described herein is directed to method of treating chronicobstructive pulmonary disease, comprisingadministering an effective amount of an osmolyte by at least one nasal cannulato a subject in need thereof. Also provided is a nasalcannula system for delivering an osmolyte, comprising a nebulizer and tubinghaving two ends, where the first end of the tubing isconnected to the nebulizer and the second end of the tubing is tapered to fitin the nostril of a subject.
